Since there is still a lack of very solid evidence of clinical effects and the molecular mechanism of hydrogen biological action, basic and clinical research on hydrogen medicine will continue.

The diffusion ability of hydrogen is very strong, but if you want to understand the basis of the effect of hydrogen, you must understand the concentration of hydrogen in tissues and cells, especially the law of changes in various tissues and cells after use. In this respect, the detection methods and strategies need to be optimized and improved.

Most research papers belong to animal model studies, which are relatively low-end evidence in evidence-based medicine. In order to promote the clinical application of hydrogen, evidence from multi-center large-scale double-blind controlled clinical studies is required. Of course, for long-term considerations, terminal clinical trials are required Evidence of treatment effect. The safety of hydrogen is relatively high, which provides an important prerequisite for the clinical application of hydrogen. However, many clinical scholars currently do not realize the special advantages of hydrogen therapy, and the motivation for clinical research is still insufficient. In addition, the lack of funding and policy support from the state and large research institutions is also an important issue affecting the clinical research of hydrogen medicine.

There have been many uses of hydrogen as a tool to treat diseases. The common ones are breathing hydrogen and drinking hydrogen water. These methods have their own characteristics. For example, hydrogen water is more convenient and beneficial to ordinary patients, but the solubility of hydrogen is relatively low, which means that this method cannot achieve the purpose of human body ingesting a large amount of hydrogen. Although breathing hydrogen can increase the intake of hydrogen, there are problems such as complicated operations and certain risks, which require relatively high technical support. More importantly, these methods have different ways for hydrogen to enter the human body, and the effects may be different. This needs to be answered by further comparative studies. For specific patients and target groups, dialysis, intravenous injection and bathing are also worthy of in-depth study.