• The development of hydrogen in Japan
    The development of hydrogen in Japan Aug 21, 2021
    Related scholars in the field of hydrogen medicine research in Japan have been committed to clinical scientific research and applied research of hydrogen for a long time, and have achieved remarkable results. Here are a few medical studies. These medical studies are not only in terms of disease treatment, but also infer that hydrogen has an effect on the improvement of daily life quality and disease prevention. ◆ The therapeutic effect of hydrogen: the effect on ordinary people -Published research in Japan ◆ Drinking hydrogen water can inhibit the rise of lactic acid of athletes after exercise and relieve muscle fatigue. ——Sports Science Paper of University of Tsukuba, Japan ◆ Hydrogen bath can relieve muscle pain after exercise. ——Sports Science Paper of Waseda University, Japan ◆ Drinking hydrogen water can relieve fatigue in daily life. ——Institute of Physics and Chemistry, Osaka City University, Japan ◆ Drinking hydrogen water can increase blood flow-mediated vasodilation (increase blood flow). This also shows that it has the effect of inhibiting arteriosclerosis. ——Thesis of Hara Doi Hospital, Fukuoka, Japan ◆ Drinking hydrogen water improved the pre-diabetes symptoms of six people. ——Thesis of Kyoto Prefectural Medical University, Japan ◆ Drinking hydrogen water can improve periodontal disease. ——Thesis of Okayama University, Japan Hydrogen therapy is officially included in the "Japanese medical system" On November 30, 2016, the Ministry of Health, Labour and Welfare of Japan included the "Hydrogen Inhalation Treatment of Cardiac Arrest Syndrome" into the "Japan Advanced Medical Class B" system. This is the first official certification for research on hydrogen as a drug, and this certification is also a great affirmation of hydrogen medicine and a great encouragement to hydrogen medicine research experts and scholars around the world. The inclusion of hydrogen inhalation as a medical item opened a new era of hydrogen medical research. Previously, many scholars believed that in medical practice, inhaling hydrogen gas for patients undergoing heartbeat resuscitation can protect brain functions and maintain life, so that they can recover quickly. This is a revolutionary medical treatment. The Ministry of Health, Labour and Welfare of Japan (Japanese: こうせいろうどうしょう) is the main department in charge of health care and social security. The Ministry of Health, Labour and Welfare has 11 bureaus and 7 departments, which are mainly responsible for Japan's national health, medical insurance, medical service provision, medicine and food safety, social insurance and social security, labor and employment, and social assistance for vulnerable groups. The same as our country The former Ministry of Health. Japan’s "advanced medical" certification is a treatment method in the research and development trial stage based on the prerequisite of being included in the pharmaceutical system applicable to Japan's health insurance. More generally speaking, hydrogen is r...
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  • Six directions of hydrogen in the future
    Six directions of hydrogen in the future Jul 14, 2021
    Since there is still a lack of very solid evidence of clinical effects and the molecular mechanism of hydrogen biological action, basic and clinical research on hydrogen medicine will continue. 1) The molecular mechanism of the effect of hydrogen Hydrogen can change the expression of many proteins and genes. In particular, hydrogen can inhibit or change the expression of related proteins and genes such as inflammation, allergies, apoptosis and oxidative stress. These molecules change significantly in the course of a variety of acute and chronic diseases. The question here is the molecular mechanism through which hydrogen regulates the expression of these proteins. I believe this is one of the core issues that many laboratories interested in hydrogen medicine consider daily. 2) Molecular target of hydrogen Hydrogen acts as targets on various cell receptors, cell membrane levels, protease activity, protein synthesis and gene expression regulation. Taking into account the complexity of biological systems, these studies should achieve breakthroughs through cellular and molecular research, using biochemical methods or biophysical methods. 3) Analysis of hydrogen concentration at the cellular level The diffusion ability of hydrogen is very strong, but if you want to understand the basis of the effect of hydrogen, you must understand the concentration of hydrogen in tissues and cells, especially the law of changes in various tissues and cells after use. In this respect, the detection methods and strategies need to be optimized and improved. 4) Clinical research needs to be strengthened Most research papers belong to animal model studies, which are relatively low-end evidence in evidence-based medicine. In order to promote the clinical application of hydrogen, evidence from multi-center large-scale double-blind controlled clinical studies is required. Of course, for long-term considerations, terminal clinical trials are required Evidence of treatment effect. The safety of hydrogen is relatively high, which provides an important prerequisite for the clinical application of hydrogen. However, many clinical scholars currently do not realize the special advantages of hydrogen therapy, and the motivation for clinical research is still insufficient. In addition, the lack of funding and policy support from the state and large research institutions is also an important issue affecting the clinical research of hydrogen medicine. 5) Compare the advantages and disadvantages of various hydrogen supply methods There have been many uses of hydrogen as a tool to treat diseases. The common ones are breathing hydrogen and drinking hydrogen water. These methods have their own characteristics. For example, hydrogen water is more convenient and beneficial to ordinary patients, but the solubility of hydrogen is relatively low, which means that this method cannot achieve the purpose of human body ingesting a large amount of hydrogen. Although breathing hydrogen can increase t...
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  • 10 Questions and Answers for Hydrogen Molecular Medicine
    10 Questions and Answers for Hydrogen Molecular Medicine Jul 14, 2021
    1. What is hydrogen? Hydrogen is the first element in the periodic table of chemical elements. Hydrogen is the smallest molecule known in nature. It generally exists as a gas. Because of its small molecular weight, hydrogen is lighter than air. It can be filled into hydrogen balloons as a means of transportation and flight. It has fast movement speed and strong penetrating power. It can penetrate more than ten centimeters of steel plates under high temperature and high pressure. Strong penetration is an important feature of hydrogen. Because of this feature, hydrogen is more difficult to store. Therefore, after dissolving hydrogen in water, if you want to maintain the hydrogen concentration in hydrogen water for a long time, you need to use aluminum alloy materials to make packaging, and other steel materials Neither glass, plastic, etc. can prevent hydrogen from escaping. On the other hand, because hydrogen is very small and has strong penetrating power, it can easily reach various parts of the body and the inside of tissue cells after entering the human body. For example, hydrogen can reach the mitochondria in the cells. The fine structure fundamentally adjusts the cell state, this advantage cannot be achieved by many drugs. 2. Where can hydrogen be used? Hydrogen can be burned to release energy to produce water. It is a very clean and pollution-free energy source. There are now hydrogen energy vehicles and airplanes. During diving, you can breathe high-pressure hydrogen gas to resist the pressure of water on the body. Hydrogen has been studied and applied in the diving field for more than 80 years. It is a safe gas for diving, and no adverse effects on the human body have been found. With the deepening of the understanding of hydrogen applications, the application of hydrogen in the fields of medical and health and agriculture continues to expand. There are large application examples in the fields of medicine, agriculture, and animal husbandry, and there are very good application prospects. 3. How was the therapeutic effect of hydrogen on diseases discovered? In 2007, Japanese scientist Professor Naruto Ota published an article in the international authoritative journal Nature Medicine, proving that 2% hydrogen inhalation can treat stroke, opening a new chapter in hydrogen medical research. In 2008, the team of Professor Sun Xuejun of the Second Military Medical University published the second international and first domestic hydrogen medicine research report. Professor Sun Xuejun is the most important advocate and promoter of hydrogen medicine research in China, and he is known as the "China's No. one person". In 2017, Professor Xu Kecheng, the general dean of Guangzhou Fuda Cancer Hospital, created a hydrogen molecular medicine experience hall for hundreds of people to provide free hydrogen inhalation and rehabilitation experience for the majority of cancer patients, and achieved great clinical results in hydrogen-assisted cancer rehabilitat...
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